GLP-1 Medications: What CQ Med Gym's Board-Certified Physician Wants You to Know

By a Board-Certified Physician

Dr. Glenn, D.O 

GLP-1 receptor agonists have become one of the most talked-about advances in modern medicine, often discussed in the context of weight loss, but originally developed for diabetes management. As a board-certified physician, I believe it’s important to cut through the noise and provide clear, evidence-based information so patients can make informed decisions about their health.

What Is GLP-1?

GLP-1 stands for glucagon-like peptide-1, a hormone naturally produced in the gut. It plays several important roles in metabolic health, including:

• Stimulating insulin release in response to food

• Reducing glucagon secretion (which lowers blood sugar)

• Slowing gastric emptying

• Increasing feelings of fullness and satiety

GLP-1 medications are designed to mimic this natural hormone, enhancing these effects in a sustained and therapeutic way.

Why Were GLP-1 Medications Developed?

GLP-1 receptor agonists were originally approved to treat type 2 diabetes. Over time, clinicians observed additional benefits—particularly significant weight loss and improvements in insulin resistance, blood pressure, and cholesterol markers.

Because of these effects, several GLP-1 medications have since received FDA approval for chronic weight management in patients who meet specific medical criteria.

How GLP-1 Medications Work in the Body

GLP-1 medications work through multiple mechanisms:

1. Appetite Regulation

   
   

   They act on appetite centers in the brain, reducing hunger and food cravings.

2. Slower Digestion

   
   

   By slowing gastric emptying, patients feel full longer after meals.

3. Improved Blood Sugar Control

   
   

   Insulin release becomes more efficient, especially after eating.

This combination supports sustainable metabolic change, not just short-term weight loss.

Who May Be a Good Candidate?

GLP-1 therapy may be appropriate for patients who:

• Have type 2 diabetes

• Have obesity or overweight with weight-related health conditions

• Have struggled with weight loss despite lifestyle changes

• Have insulin resistance or metabolic syndrome

That said, GLP-1 medications are not appropriate for everyone. A full medical evaluation is essential before starting therapy.

Potential Side Effects and Considerations

Like all medications, GLP-1 therapies come with potential side effects. The most common include:

• Nausea

• Vomiting

• Diarrhea or constipation

• Decreased appetite

These symptoms are often dose-dependent and temporary, especially when medications are started slowly and titrated appropriately.

More serious risks, though rare, must also be discussed, including:

• Gallbladder disease

• Pancreatitis

• Thyroid-related concerns in specific populations

This is why GLP-1 therapy should always be prescribed and monitored by a qualified medical professional.

GLP-1 Is a Tool Not a Standalone Solution

One of the most important points I emphasize to patients is this:

GLP-1 medications are a tool, not a cure.

The best outcomes occur when medication is combined with:

• Nutrient-dense eating

• Strength training and movement

• Adequate sleep

• Stress management

• Ongoing medical follow-up

Used appropriately, GLP-1 therapy can help reset metabolic pathways and support long-term health but it should never replace foundational lifestyle habits.

A Physician’s Perspective

As a board-certified physician, my goal at CQ Med Gym is not simply weight loss—it is improving overall health, reducing disease risk, and enhancing quality of life. GLP-1 medications can be life-changing for the right patient, but they deserve thoughtful prescribing, proper education, and individualized care.

If you are considering GLP-1 therapy, have an open and honest conversation with a medical provider who takes the time to understand your full health picture.

Medical Disclaimer:

This article is for educational purposes only and does not replace individualized medical advice. Always consult your healthcare provider before starting or stopping any medication.

Dr. Brittany Glenn M.A., D.O

Emergency Medicine Physician 

ABOEM Board Certified